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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe7b8a3292969c775b8f21126b8b1897d8303b581857d3b77bcc7ff4b541050' 
  AND token = 'vfa1lQvGm3LXFOJpVa83jiQtQdJHUVaQ2vSW/iLjCm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}