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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716aa48f0c62e537fc67ffacfd23f373074cb1d96db82632ad6c2cc701e3d1b7' 
  AND token = 'pYVjG7kNnnofBh3/TaQX/xeUdVUEmkyt/vWYLtM6TdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}