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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6331bb3b8c2f11ae4f3be4715132c3998aeb36522e15abdd9d9562552767a2' 
  AND token = 'ZC83Sq0+9TLt5S2XW5laQ34EaVcbqQlQ5Ie0kLxYCao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}