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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de612e1c4d8e55d83244bc5f7eac51190e74dd2593153e0a92f9df57695b7c81' 
  AND token = 'ozDt/qXfWADTFJSk4wz/xNx5vwgSR0V9ZHAkLVUFS8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}