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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4f85d0e0911aaf24748cc1e73c025fbf9ed0745ae04f9b48620ead577eaedc' 
  AND token = 'Xpj2UkJ16fIire7kK9D42obui66+NNb48YvGKE9crqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}