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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b653e9768c8cac67785734c02cde135b8259b2ac2aa423da78e70ee8d73e9bd' 
  AND token = 'xQOE0TjJDmNG+xkInKGX1eVQDKiRefabbzaFmoSFu6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}