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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94ee11e3a40bfe10f23949258f7f4d891247a87e1289eaea186cfab4bf29c7bd' 
  AND token = 'zmZ59XD46wcmgrGtsWON+RQ7Q8snkDsdma0U1jQI65Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}