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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6167f8e2265b9ed7593033be5d11d20f559cc5fc40c14c1124d0aab03ea8f787' 
  AND token = 'RzQeylxe9PRb3ClR3ZQKle1X4iwqwbgteKSMM+NOSco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}