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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c2dc27365d9e558be5dba3aea19c83fbaeadf8674f436fe5276506c424ed53' 
  AND token = 'qlsKZrIZ748Ylf0u6m9yl4b+6txajgVWvqZP+6LJEbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}