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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4a5ebf88703ab04623296d54ac7db550d130299e458a0366f2e9ba2d447cca' 
  AND token = 'RiPik3b8ALWgeqLLVEvmQZ0CkfUcMViccRiqnoZAVt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}