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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181cf5996a08bf2ec914a8d79ca5926199d95e547d975c7c0bb44a4b018ec7be' 
  AND token = 'Q3yqySNPi6rl0t2vZU46HyJ8XcZPZ9kBNIH8NdbcfpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}