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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc262959d79ccaa1840729931bb7a1ea1580016019a9986bbf363d6e822ec36' 
  AND token = 'wjGRXj5Jt01GaJQ/C9eIkiNio+hRrULNv91LP47dA0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}