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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d82bf150e0f93b42660de9848b938afd065c5e9fce0d8ee70101afe3cb0583' 
  AND token = 'FORULR4HDIXmKWNtxMfBhol4RmEzyyMxx2z3MG5B1No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}