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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2801deb359e39a7e72a3720e78f44eadff4bdb97cf592a63f2c304005b08b51f' 
  AND token = '6o45XjOY2M89/YVQ+MWKQfdgwTcI97YIi7qZif8Aftk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}