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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05937dbfe3260b674f4a232d10c197a08c838ccdaf64f9e1fc01c3c12e88e0dd' 
  AND token = 'pFVt7kC9OeIZigY4xr80thXDXyRq1Y5n3rXgwWff4qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}