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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21aa30483d467816cca40fad6d12207bfc09af4fd1d86178f5dbdfb10ccf08b0' 
  AND token = 'zktHX0xmoTVI9ezgmcN+ioxKz8kpEpK2x4OzZqGoPbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}