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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f52c6522078e084c08f976fd33e00d13101decad9f870b5dbb0b032a440bbe' 
  AND token = 'zugiE1r3+vzUWl1csmhrVBlG/fDHRePxB122Kw+NSy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}