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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01afe3e5cae1dcb6a669c1768f8d23f114d1b94eda8bc58678ea179a64d61b6' 
  AND token = 's4KZc/t0KIBgLqqkCs0UEu0gajdFofzg9Ys3HWnmOh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}