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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18874f23cc599ea43a4d314cb82b1d1a4b8ad46e72d71a7b337c720d7f1c7f80' 
  AND token = '1y/xtPfcY8lgZ/IqEBL4Ovs6RoamSGOt96p6Yu48/Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}