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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b72b6b796e5f679c9f936ede80f5444c22b82b8f0fbbfa9c2e5ca751c8d21e4' 
  AND token = 'kc6FBVEdL1utVUBvKnS2rvEQWpSQb9/7F0y4ivE38zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}