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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60dffab1467eebeb7dcb7c9cb799b25047a8deb4fdcd3bb8e5283cb55bd03d61' 
  AND token = 'trvJp5HAVbC0Obuv7GQ+ixOJzCGmExYdGkcSq0hbBf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}