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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1662b21070ece211428f568882b68d006f307622ce377523a624efafbe781e15' 
  AND token = '8nGq4AmP+BkaP3xvC40+aXqHrmBPGWA1o5vrHio1HMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}