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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0148e4e2885a631e2260d81fbd04701b5805c53c784ae203fcc180fd6b348738' 
  AND token = 'sSqi7iCI3Xqte3B2v83RqzDIN2hCVrFH/XEgW1Wp6lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}