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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e661c8c8b0b51600207e0c245c9155db51c8f425c545fc2a8deeae89302b767f' 
  AND token = 'BumAYEyY0oFyNrbF5EwprTmRCiGyF97c4MdCfbx+cJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}