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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0053bdbaf0831914d071cced85f7e38273a0a65567473eb14d0a82698c45b473' 
  AND token = 'Ye1VAHKmOJyCvhOb4tX2pTiyWiYIbRVl4r7KdxK3iP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}