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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25da9aed5baff0c72cb1793960ed9e4be1b4488c5a60360cf12ccf778d20f0c' 
  AND token = 'f/JeTBA0w+fQU4NrVQ07w1o4LUh5Ik+pmWBIKhn7Hnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}