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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c65a9951254c51206b55048054b30544a3a99375a6a80b44aab79de35adc21' 
  AND token = 't78jShJ55jomJaqJBWn2RXrRTYLLc+JVv8ULh2Bgj4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}