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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e380f4b4377c3ce73f51bf3f03a1899c2ecd0744fe3fff020e10f01bfd0645f' 
  AND token = 'mZ/vNYraZUFczI88bBXOApHKmKh6FARVXpMvHh10naY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}