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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758fbfc43637175ecf0528f058d10f5aac82919197621de429ca01b4723f7a61' 
  AND token = '+MC8hRg3zUkhywfE8xcs1pgQgaB2qe/6UTyq0niqyGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}