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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32cd1344aadf15821ff1d605eaf93c070be22eb2590896b6e00a5316f67125a6' 
  AND token = 'ECwEpoZi2hMa/hLMFjtZaOe6uDbDeYOgOY/Gbx/FxO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}