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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6952381df33d085b7bf54a1cecd91f9bb3a2a6e75ffab738878a6976c23da06b' 
  AND token = 'de15G96EtJZfKWc+X7kES+WehTDhVbjouLpxowFz4bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}