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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5117e2ac394d21dcb2091a02942b0c37fdc8bcba2c6529975c8c29a405fcbf0' 
  AND token = '9sAUxs2aSq4N5L/U2YZglfYwIjp+AFPLaQlCxMSbrCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}