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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f53ad5557537395e4ca110503f2d6c5a1eb3d79a64643053a5c046fbae6f425' 
  AND token = 'xd4R5pVTCZ6RMetetCpuWbxG7me21rVZJuCV4orBT08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}