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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60211c2ace95d58252789270da7f8e1437a94f69a03c0b284199aec14894f183' 
  AND token = 'QsPdEgmt+N7oqQPOKLruOlp8E6QjnhaSpaaE6o/2qeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}