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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd64d46c79d073a50d470115f76c704f662ce6ed339cbe9cd5ed639f686b60c6' 
  AND token = 's7O7sXsB6JKYCMCYmfDLOG4vkA9ldhO2Uvv4Xo8lEng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}