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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fcddb156c9e8b208d50bf08ac7e7ae5870af1309497198aa3063cece333d482' 
  AND token = 'ghEDj7jmSeK2dFAcBys/tPeM7o+FZX0zRVX2YnTL4FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}