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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3a78f27ad73c45e625108301bc61d8ba283106e4ea0cd90814a5046aa3a373' 
  AND token = '9omVBOH0Goe3+PqbaNRtVjYsDlBHfbJIq/l6s34/uLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}