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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37369f8120f13d2633be1114e00a55fa2ce27de42754be694f0120636b546093' 
  AND token = 'lZi6ELU/nXe9aRZp4vVGbvI/2j1dkyTpd1c+yTDhw/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}