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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d2d66dbbb9017f8e8cea200ad0030ca8a5f5d32077dd99033a58e6e0156790' 
  AND token = 'DdyI+VPLGiJMePIyY1AdOfbIAI1B+8a16mSfXWGYBbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}