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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d5d4e69136a5f44b374429016f9e9a42976e98720f8dfb3e036ef4e8124e49' 
  AND token = 'SB0c6gW6VoFGOy0b38rXrMlPXIYbtUj1aC3lm8mrIC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}