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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e49cc9eb40a2aeae25b9580249f33221fc6c0f682d0c5915c2617b2ee3eb40' 
  AND token = 'GqrpoUMRgk8dq2+fPEJG5YKddYq4yrmCLpM5JYwLXms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}