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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d1e95180e5324108807e0e882a9a4b1eda18cac4c10b3f02d120807d4bf92c' 
  AND token = 'ga0dUzj8A0iRzq1b+9MK7mulXO1piZ0NeSAHdYvkl6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}