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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e61f644c3114f867f48bd958a21733d87a37a546a9141f5accc57b82276065d' 
  AND token = 'R5XW5dtnEsvNTACaQcRLP+ew/B0f1hHoH6MFRja+Nz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}