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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf69d4ff464271f8f6c6d051fece92fca15cbcc764da8163b36e1789c804e06' 
  AND token = 'sWFl5rVMOZgnmBkzyLU1heTHwOQPhdNT+VM2BGSOab8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}