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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49afe9ab57e5b1112f74b7dc04f067c8801d78af456af8a4a78590830a6a19b' 
  AND token = 'Fi3vaPnV0sRNj6/tdGFbrRHotBCsBH1W4nN5WmMJjXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}