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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d96a05957d38edfddfbe1c79a3bdf0c1f47cc451cfc651b712bb7ef8cb546ad' 
  AND token = 'jEtARMO4oMlhJtqtJGF1nBuQ9AHlxvOEFKhuJQpSlqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}