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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4872b55adaf7caa65ec7cdeec5a148906ea22f3be25a5c93974c8499d6a91c05' 
  AND token = 'U1WoRBjKlYZ8sQYd8jC9WNPQ/t4Brj7Aiz7IKA9zZls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}