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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e5d253cf933dc563478c6d67ddb075c3f69831b92ddcc2b5c522a1cc765a44' 
  AND token = 'Dgd3p8jL54vyQdgxlUjZGN1Q0GAObM8zIQ8AKgCGl4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}