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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f40d3abfd16f4d21f36db8696cafc4b69505669d91a546c53314dc54275d0f9' 
  AND token = 'ewQcmdfM/8iz7qrKh1ad46+TsrnTl7XzJe2s4+h9LOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}