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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a0f3000c99d6459fc9c98081f40e6c1ee4d6498f297402ba26b58aa475c859' 
  AND token = 'nz7gbgn8kYkgnY6HKmOAUrt24xoGdWrKkUBZp28pz/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}